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Pukyong National University Professor Nam Seung Yun’s Team Develops Elasticity Monitoring-Based Bioprinting Technology- World’s First Real-Time Elasticity Monitoring-Based Bioprinting Technology Pukyong National University (President Bae Sang-Hoon) announced that the research team led by Professor Nam Seung Yun of the Department of Biomedical Engineering has developed a new bioprinting technology using ultrasound elasticity monitoring. Professor Nam Seung Yun, along with Professor Park Sang-Hyug from the same department and Professor Yoon Changhan from the Department of Biomedical Engineering at Inje University, successfully developed the world’s first technology that precisely measures the elasticity changes of cell scaffolds in real-time during the bioprinting process using ultrasonic shear wave elastography. Bioprinting is an advanced technology for tissue regeneration and artificial organ development, but there have been limitations in precisely evaluating the mechanical properties of cell scaffolds in real time. Human tissues have varying elastic properties, and since the growth and differentiation of cells are greatly influenced by these mechanical characteristics, the development of a technology to dynamically monitor them is essential. Conventional methods can only assess the mechanical properties destructively before and after the fabrication of the cell scaffold, making it difficult to capture dynamic changes during the bioprinting process. However, the technology developed by the research team has the advantage of enabling non-destructive monitoring of the elasticity and stability of the structure even during the fabrication of the cell scaffolds. The research team published their findings in the paper titled “Suspended bioprinting with in-situ elasticity monitoring using the assessment of shear wave phase velocity” in the top-tier international journal
Pukyong National University Key Research Institute’s Research on Anti-Cancer and Anti-Bacterial Properties of Seaweed Gains ‘Attention’-Synthesis of Functional Silver Nanoparticles Using Phytonutrient-Derived Substances Published in International Journal The research team from the Marine Bionics Convergence Technology Center (Director Jung Won-Kyo), a key research institute of Pukyong National University, has gained attention for synthesizing silver nanoparticles (AgNPs) using seaweed-derived substances and demonstrating their anti-cancer and anti-bacterial properties. The team used phlorotannin, a polyphenolic compound isolated from brown algae species, and synthesized functional silver nanoparticles (AgNPs). They presented the results of the synthesis mechanism through optimized synthesis processes, anti-cancer and anti-bacterial activity evaluations, and molecular dynamics simulations. The silver nanoparticles successfully synthesized through the optimized process exhibited excellent anti-cancer and anti-bacterial effects in the experiments conducted by the research team. The team also performed molecular dynamics simulations to predict the phlorotannin and silver nanoparticle synthesis process at the molecular level, identifying the nanoparticle formation process and pH-dependent molecular behaviors. The research team included the first author, Ph.D. candidate Kim Nam-gyun (Department of Industry 4.0 Convergence Bionics Engineering), corresponding author Professor Jung Won-Kyo (Department of Biomedical Engineering), co-author Professor Yi Myunggi (Department of Biomedical Engineering), student Lee Hye-won (4th-year Biomedical Engineering), Master’s student Hadi Sedigh Malekroodi (Department of Industry 4.0 Convergence Bionics Engineering), Professor Kim Young-Mog (Department of Food Engineering), and postdoctoral researcher Oh Do Kyung (Department of Food Engineering), all contributing to the successful collaborative interdisciplinary research. The research paper titled ‘Harnessing marine-derived polyphenols for the one-pot synthesis of functional silver nanoparticles: Anti-cancer, anti-bacterial, and MD simulation’ was published in the prestigious international journal
Pukyong National University and She’z M Co., Ltd. Collaboration on ‘AI Bidet’ Technology Draws ‘Attention’-Professor Kwon Gi-ryong and CEO Kim Bo-seong’s research team … Selected for outstanding corporate performanceThe ‘AI Bidet’ technology jointly developed by Professor Kwon Gi-ryong (Department of Computer and Artificial Intelligence Engineering) at Pukyong National University and CEO Kim Bo-seong of She’z M is receiving attention. The ‘AI Bidet’ developed by Professor Kwon’s research team is an AI-powered restroom system that uses artificial intelligence algorithms to analyze bathroom habits, including both urination and defecation. This system incorporates innovative technologies that utilize a combination of video analysis, chemical analysis methods, and sensors with artificial intelligence algorithms to monitor the user’s health status and provide feedback. After using the toilet equipped with this system, the user presses a button, and the sensor measures the intestinal health condition, which is then relayed to the user through a mobile app, allowing them to systematically manage their gut health. CEO Kim Bo-seong of She’z M entered Pukyong National University’s graduate school in 2022, completed his master’s program, and worked alongside Professor Kwon Gi-ryong’s research team to develop this system. She’z M, with this technology, was selected for the “Top 50 Outstanding Achievements in R&D by SMEs” by the Ministry of SMEs and Startups in 2023, winning the Minister of SMEs and Startups Award. Furthermore, in 2024, it was recognized as a contributor to the development of the medical industry in Busan at the 2024 Medical ICT Convergence Center Performance Report held on December 17 and received a commendation from the Mayor of Busan. She’z M has commercialized the technology and released it as an actual product, entering the domestic and international bidet markets in collaboration with bidet rental companies. CEO Kim Bo-seong stated, “By focusing on the routine of using the restroom in the morning, we developed AI technology to analyze biomarkers within the toilet. We will continue our research and development to introduce innovative products that contribute to users’ health management.”
대외홍보센터 (2025-02-18)조회수 123Pukyong National University, Develops the First Domestic Fish Stock Quantification Method Based on eDNA-Professor Kim Kyung-hwe’s Research Team Publishes Findings in International Academic JournalPukyong National University (President Bae Sang-hoon) announced that Professor Kim Kyung-hwe’s (Department of Ocean Engineering) research team has developed the first domestic fish stock quantification method based on eDNA. Professor Kim Kyung-hwe from the Department of Ocean Engineering at Pukyong National University, along with Ph.D. candidate Park Seong-sik and Dr. Yoon Seok-jin from the National Fisheries Research and Development Institute, conducted a numerical study on evaluating fish population and distribution in semi-enclosed bays using the environmental DNA (eDNA) approach. eDNA is an innovative method that uses genetic traces of organisms to extract ecological information, and it is considered more efficient and non-invasive compared to traditional survey methods. In this study, the research team analyzed the impact of environmental factors such as water temperature and currents on the distribution and concentration of eDNA through numerical modeling, and assessed the accuracy of the eDNA approach in estimating fish distribution. Through this study, the research team not only demonstrated that the eDNA-based approach is a useful tool for estimating fish stock in semi-enclosed bays, but also presented new possibilities for fisheries and marine ecosystem management. The paper titled ‘Numerical Study on Evaluation of Environmental DNA Approach for Estimating Fish Abundance and Distribution in Semi-Enclosed Bay’ has recently been published in the SCIE international journal
Professor Se-Jung Lee's Team at Pukyong National University Developed Metformin-Based Treatment for ColitisPukyong National University (President Sang-Hoon Bae) announced that the research team led by Professor Se-Jung Lee from the Department of Smart Healthcare Convergence, Human Bio-Convergence Major, has developed an innovative metformin capsule effective in treating inflammatory bowel disease (IBD) and improving the gut microbiome. Professor Se-Jung Lee collaborated with Professor Chang-Hyung Choi from Yeungnam University, and the joint research findings were published in January in the international journal Journal of Controlled Release (IF 10.5), which specializes in chemistry and pharmacology. The research team developed an oral pH-responsive drug delivery system using microfluidic technology to encapsulate metformin, a well-known diabetes treatment, within a triple-layer hydrogel capsule. This capsule is designed to release metformin specifically in the colonic inflammation site (pH 7) while protecting the drug from degradation in the acidic gastric environment (pH 2). This approach significantly enhances the bioavailability of the drug at the target site, enabling effective treatment of inflammatory bowel disease (IBD) with lower doses. The study also revealed that metformin not only regulates the pro-inflammatory immune response mechanism in IBD animal models but also improves the diversity and richness of the gut microbiota. Professor Se-Jung Lee explained, “Patients with inflammatory colitis often face dietary restrictions, which can impair nutrient absorption, disrupt glycemic control, and increase the risk of developing Type 2 diabetes. While metformin has garnered significant attention as an exceptional diabetes treatment, its potential as a colitis treatment remains largely unexplored. Moreover, its stability and bioavailability are often compromised due to degradation by gastric acid and digestive enzymes before reaching the intestinal tract, necessitating higher doses. This encapsulation technology addresses these limitations and represents a breakthrough in drug delivery.” He further emphasized, “Our findings highlight metformin’s novel pharmacological effects and its potential as a therapeutic option for microbiome modulation and the treatment of refractory colitis through microcapsulation technology.” Additionally, Professor Lee shared his aspirations, stating, “Through the development of advanced microcapsules and microneedles, I aim to discover biopharmaceuticals, such as stem cells, peptides, and antibodies, capable of being specifically delivered to disease sites. This research will contribute to treating metabolic, chronic, and intractable diseases. I also hope to foster the next generation of talent in the field of smart healthcare.”
대외협력과 (2025-01-21)조회수 220Pukyong National University Research Team Discovers Anion Separation Phenomenon in All-Solid-State Batteries-Research by Professor Jeong Seong-cheol’s Team Published in the UK Royal Society of Chemistry Journal-Localized Anion Separation Phenomenon Causes High Ionic Conductivity Pukyong National University (President Bae Sang-hoon) announced that Professor Jeong Seong-cheol’s (Department of Physics) research team discovered a phenomenon in which monovalent and divalent ions are locally separated in the Li6PS5Cl solid electrolyte of the argyrodite structure used in all-solid-state batteries. The research team, led by Professor Jeong Seong-cheol, Postdoctoral Researcher Lee Se-ho (G-LAMP Project), and Ph.D. student Jeon Tae-gon (Department of Physics), revealed through first-principles calculations that the difference in lithium mobility due to the anion domain caused by the anion local separation discovered in the Li6-xPS5-xClBrx solid electrolyte is the cause of the high ion conductivity in the Li6PS5Cl series solid electrolytes. Solid electrolytes based on the argyrodite structure have excellent ion conductivity, good cost-effectiveness of raw materials, and ease of synthesis, leading to active research in this field. Professor Jung’s team found that in this study, lithium ions are more concentrated in the S2- divalent anion region than in the Cl- and Br- monovalent anion regions, leading to the effective stabilization of the argyrodite structure. Additionally, lithium ions in the divalent anion region showed low mobility due to their strong binding with the anions, while lithium ions in the monovalent anion region exhibited higher mobility due to weaker binding with the anions. Through this, they identified that the lithium diffusion mechanism in argyrodite solid electrolytes relies on the anion regions. Professor Jung Seong-cheol stated, “This study reveals that the well-known disordered arrangement of anions in Li6PS5Cl-based argyrodite solid electrolytes is actually related to the local separation of anions, providing a new perspective for understanding the high conductivity of argyrodite solid electrolytes.” Meanwhile, this research was conducted with support from the Ministry of Education’s G-LAMP project and was recently published in the prestigious international journal
Pukyong National University Professor Kim Young-mok’s Research Team Publishes Paper in Top Environmental Engineering and Safety Journal-
Pukyong National University Professor Kwon Hyuk-jin’s Research Team Develops Low-power Driven Printed Flexible Transistor Electronic DevicesPukyong National University (President Bae Sang-hoon) announced that Professor Kwon Hyuk-jin’s research team (Major of Industrial Chemistry) has developed polyimide-based gate dielectric technology, which is being recognized as a key material for next-generation flexible electronic devices. Professor Kwon Hyuk-jin, along with Professor Lim Bo-gyu, Chungbuk National University (Major of Industrial Chemistry), Professor Kim Se-hyun, Konkuk University (Department of Chemical Engineering), and Professor Lee Seung-woo, Yeungnam University (Department of Chemical Engineering), and the collaborative research team, published their findings in the materials science international journal
‘COVID-19 Strengthens Internet Social Networks Among Black College Students in the U.S.’- Research Findings by Professor Lee Eun of Pukyong National University A study has found that during the COVID-19 pandemic, the reciprocity of internet social networks among Black college students in the U.S., who expressed feelings of depression, has been strengthened. Professor Lee Eun (Department of Scientific Computing) at Pukyong National University has published the paper titled ‘Internet-Based Social Connections of Black American College Students in Pre-COVID-19 and Peri-COVID-19 Pandemic Periods: Network Analysis’ as the lead author in the latest issue of the international journal
Pukyong National University, ‘Attention’ to Research on Antibiofilm Applications of Marine-Derived Substances-Professor Kim Young-mok’s Research Team … Published in the Prestigious Journal , a Sister Journal of
First Discovery of a New Species of Ttibyeolbaragi (Limnichthys koreanus) in South Korea-Research Team at Pukyong National University Reports First Subtropical Species of Creediidae in South KoreaResearcher Lee Yu-jin from Pukyong National University (Ph.D. Candidate in Marine Biology) published a new species, ‘Ttibyeolbaragi (Limnichthys koreanus),’ in the October issue of the prestigious international journal in zoology, . The paper is titled ‘Limnichthys koreanus, a new species of creediid fish (Teleostei, Acropomatiformes, Creediidae) from Korea’ (Advisor: Professor Kim Jin-goo). The newly reported species, Limnichthys koreanus, is a small fish measuring less than 5 cm, collected by Professor Kim Jin-goo while skin diving in Moseulpo, Jeju Island. This is also the first time that a subtropical species of the Creediidae fish has been reported in South Korea. The Creediidae family has never had a single species reported in South Korea, making it a taxon with no biological information available. In a study where researcher Lee Yu-jin raised Limnichthys koreanus in a laboratory tank for three months, it was found that the fish has a unique behavior of hiding in gravel and sand, then leaping at an incredible speed to intercept food when small crustaceans, such as water striders, approach, before returning to its original position. Additionally, its heart rate was measured at 190 to 240 beats per minute, indicating that it can move remarkably fast despite being a small fish. The research team went through some ups and downs almost losing the species they had just discovered. Professor Kim Jin-goo initially collected this species and placed it in a collection jar with other specimens, but when he checked outside the water, he could not find it. After returning to her accommodation, researcher Lee Yu-jin shook the collection jar to examine the specimens, during which a Istigobius campbelli in the jar regurgitated the undigested Limnichthys koreanus, allowing them to confirm the species again, leading to the announcement of the new species. Professor Kim Jin-goo stated, “Limnichthys koreanus is a small fish species that lives hidden in the gravel of the shallow intertidal zone at a depth of 1-2 meters in Moseulpo, Jeju Island, and due to its unique characteristic of being found only in Jeju, there is a need for follow-up research for species conservation as well as various efforts for habitat protection in the future.” Professor Kim Jin-goo has operated the marine fish resource donation and registration preservation agency under the Ministry of Oceans and Fisheries for 11 years, and with the budget support from the National Marine Biodiversity Institute, he has achieved research results reporting the new species of Limnichthys koreanus, dedicating himself to the assetization of marine fish resources. To date, he has successfully secured over 800 specimens of native fish species, and the Limnichthys koreanus specimens have been transferred to the National Marine Biodiversity Institute for continued research use.
대외협력과 (2024-10-25)조회수 666Pukyong National University·Tech University of Korea·Sungkyunkwan University, Develop New Cancer Treatment Technology Using ‘Nano-Bubbles’-Nano-Bubbles Responsive to Ultrasound… Destroying Cancer Cell Nuclei to Treat Metastatic CancerProfessor Eom Woo-ram from the Department of Bioengineering at Pukyong National University, Professor Yoo Dong-gil from Tech University of Korea, and Professor Park Jae-hyung from Sungkyunkwan University have successfully developed a new type of mechanical cell death method(caviptosis) that can dramatically enhance the efficacy of cancer immunotherapy, marking the first development of its kind in the world. Cancer immunotherapy is a method of treating cancer by utilizing the body's immune function, and it is gaining attention for its lower side effects and superior treatment effects compared to traditional chemotherapy. In particular, immune checkpoint inhibitors, which are a representative method of immunotherapy capable of normalizing immune responses disrupted by cancer cells, are being actively applied clinically to treat various types of cancer. However, recent studies have shown that when there is a deficiency in the number of cytotoxic T cells present in the tumor microenvironment, the effectiveness of immune checkpoint inhibitor therapy significantly decreases. Consequently, there has been a continuous demand for new technologies that can attract external immune cells to the tumor site to enhance the efficacy of cancer immunotherapy and expand treatment benefits to a larger patient population. Professor Eom Woo-ram's research team focused on the role of eosinophils, a type of white blood cell. Although eosinophils are generally known to have a negative impact on cancer treatment, they can be stimulated by interleukin-33 (IL-33), which resides inside the cell nucleus, to attract immune cells into the tumor and exhibit strong anti-cancer effects. However, IL-33 is tightly bound within the cell nucleus, making treatment options utilizing eosinophils and IL-33 extremely limited. Professor Eom Woo-ram's research team successfully developed a mechanical cell death method (cavitopsis) that can rupture cells when exposed to ultrasound by utilizing nano-sized bubbles capable of penetrating into the cells. The nano-explosive agent made from nano-bubbles responsive to ultrasound ruptures the nuclei of cancer cells, releasing IL-33, which is hardly released in its natural state, into the extracellular space. This IL-33 stimulates eosinophils to attract immune cells into the tumor, elucidating its anti-cancer effect. The research team validated the therapeutic efficacy of the nano-explosive agent in a real lung metastatic cancer mouse model, confirming a dramatic enhancement in the anti-cancer efficacy of existing immune checkpoint inhibitors. The principal investigator, Professor Eom Woo-ram, stated, “Currently, cancer immunotherapy is very expensive, costing millions of won, and has limitations as it is effective only for a subset of patients. However, I expect that this research will dramatically enhance the therapeutic efficacy of cancer immunotherapy, increasing the potential for treating metastatic cancers that have been difficult to treat with existing therapies.” The research team conducted this study with the support of the National Research Foundation of Korea’s Individual Basic Research and National New Drug Development projects. The research results were published in the international journal
Pukyong National University Faculty Startup Company, Reveals the Sleep Improvement Effect of Lime Peel for the First Time- Nutraight Co., Ltd. Publishes Paper in an International Journal and Pursues Export of Health Functional Foods Pukyong National University faculty startup company Nutraight (CEO Cho Seung-mok, Professor of Food Engineering) has revealed the sleep improvement effects and mechanisms of action from the peel of lime, a type of citrus fruit for the first time. Nutraight Co., Ltd.'s research team, in collaboration with Dr. Lee Jae-gwang's research team at the Korea Food Research Institute and Professor Jang H. Youn's research team at the University of Southern California's School of Medicine, scientifically elucidated the sleep effects and mechanisms of action of lime peel. The research team, with support from the TIPS program of the Ministry of SMEs and Startups, explored globally recognized raw materials to develop high-quality sleep functional ingredients that can enhance global competitiveness. The study found that lime peel extract showed significant reductions in sleep onset time and increases in total sleep time in animal tests. In particular, it was confirmed that lime peel extract has the ability to increase deep sleep and improve sleep quality. The sleep effects of lime peel extract are attributed to the flavonoid compounds abundantly found in lime peel, which activate GABA receptors like the inhibitory neurotransmitter GABA in the central nervous system, and this mechanism of action has been scientifically proven. The research team recently published a paper containing these research results in the prestigious international journal
Revealed the Correlation Between Excessive Alcohol Consumption in Adolescents and 'Risky Sexual Behaviors'-Research Results from Professors Heo Won-bin and Oh Young-sam at Pukyong National UniversityResearch has found that as adolescents' alcohol consumption increases, the likelihood of engaging in 'Risky Sexual Behaviors' also rises. Professors Heo Won-bin and Oh Young-sam from the Department of Social Welfare at Pukyong National University presented research findings that clarify the correlation between alcohol consumption and risky sex behavior among Korean adolescents who have had sexual experiences with the opposite sex. Risky sex behaviors refer to sexual activities that do not involve contraception, such as the use of condoms. The research team conducted the study using statistical data from the 16th(2020) Youth Health Behavior Survey, focusing on 54,948 participants(from 7th grade to 12th grade). Among these, they examined 2,487 adolescents who had sexual experiences with the opposite sex, comparing 547 adolescents who consumed alcohol with 547 who did not. The research team analyzed the statistical data using methods such as Propensity Score Matching (PSM) and Multiple Logistic Regression Analyses. The results showed that the presence or absence of alcohol consumption itself was not related to risky sexual behaviors. However, when analyzing only the group that consumed alcohol (547 participants), it was found that as alcohol consumption increased, the likelihood of engaging in risky sex behaviors, meaning having sexual intercourse without contraception, also increased. In particular, when analyzing gender differences, it was revealed that the likelihood of engaging in risky sex behavior increased with alcohol consumption only among female adolescents, while no such association was observed in male adolescents. Professor Oh Young-sam stated, “To ensure proper sexual behavior and awareness among adolescents, it is necessary to establish various educational programs and protective measures regarding sex in homes, schools, and communities.” The research findings are published in the paper titled ‘The Relationships Between Alcohol Drinking and Risky Sexual Behavior Among Korean Adolescents: Focusing on Heterosexual Adolescents’ in the latest issue of the international journal
Pukyong National University · Korea Institute of Materials Science · GIST, Develop Technology to Enhance the Lifespan of Hydrogen Fuel Cells- Development of New Carbon Material Additives for Electrodes… Significantly Improved the Durability of Polymer Electrolyte Membrane Fuel CellsProfessor Seo Min-ho from the Department of Nanotechnology Engineering at Pukyong National University, Dr. Choi Seung-mok from the Korea Institute of Materials Science, and Professor Eom Kwang-seop from the Gwangju Institute of Science and Technology (GIST) research team have successfully enhanced the durability of a commercial-grade polymer electrolyte fuel cell system by utilizing a newly developed carbon material, which was created for the first time globally, as an additive in the electrode manufacturing process. Polymer electrolyte membrane fuel cells, which are gaining attention as environmentally friendly and high-efficiency batteries, generate electricity by using hydrogen as fuel through a hydrogen oxidation reaction, emitting only water as a reaction product. However, in conventional polymer electrolyte fuel cell systems, the start-up and shut-down processes generate high voltages above 1.4V, which accelerates carbon corrosion in the catalyst layer. This leads to the collapse of the catalyst layer and the phenomenon of water accumulation inside the electrodes due to the water produced during the oxygen reduction reaction (water flooding), which caused a problem with significant reduction in durability. Professor Seo Min-ho's research team effectively improved the decline in durability of fuel cells caused by carbon corrosion by utilizing a new carbon material with high carbon corrosion resistance as an additive in the electrodes. The fluorine-doped graphene nanoribbons and carbon nanotube composite (F-GNR@CNT) used in this study were developed to overcome the carbon corrosion vulnerability of existing graphene nanoribbon oxides. Existing graphene nanoribbon oxides become enriched with oxygen functional groups due to strong chemical oxidation during the synthesis process, resulting in significant defects and instability at the boundary regions, making them highly susceptible to electrochemical carbon corrosion during fuel cell operation. Professor Seo Min-ho’s research team synthesized a carbon nanotube composite with high corrosion resistance by controlling the oxidation level and formed stable carbon-fluorine bonds through a heat treatment process for fluorine doping. Professor Seo Min-ho’s research team developed an electrode manufacturing technology that optimizes the process of adding a minimal amount of the F-GNR@CNT composite in collaboration with Dr. Choi Seung-Mok from the Korea Institute of Materials Science and Dr. Choi Young-Woo from the Korea Institute of Energy Technology and manufactured the electrodes. In collaboration with Professor Eom Kwang-Seob’s research team from GIST, the durability of accelerated electrochemical carbon corrosion of these electrodes was evaluated, and the results indicated that the degradation rate in the mass transport region of the existing catalyst layer electrode was approximately 85%, while the electrode with the added new carbon material exhibited a degradation rate of about 40%, confirming a very high resistance to electrochemical carbon corrosion. The principal investigator, Professor Seo Min-ho, stated that “the fluorine-doped graphene nanoribbon and carbon nanotube composite, proven through a combination of experiments and computational science, will be an important strategy for efficiently and easily developing high-durability hydrogen fuel cells when used as an additive in electrodes. This research achievement was carried out with support from the Pukyong National University’s Young Researcher Challenge Research, the Korea Energy Technology Evaluation Institute, the Korea Industrial Technology Planning and Evaluation Institute, and the fundamental projects of the Korea Institute of Materials Science. The research results were published in the international journal
Research on Future Wireless Optical Communication Using Ultraviolet Light Gained International Attention-Professor Jeong Yeon-ho’s Team at Pukyong National University Published Paper in the Top-ranked International Journal in the JCRResearch on developing new wireless optical communication technology for the future using ultraviolet light is gaining international attention. The paper titled ‘A Comprehensive Survey on Optical Scattering Communications: Current Research, New Trends, and Future Vision’ by Professor Jeong Yeon-ho’s research team from Pukyong National University (Major of Information and Communications Engineering) was published in the latest issue (Volume 26, Issue 2) of the international journal