연구/산학
PKNU Research 1000
| Lim Hae-kyun | International Collaborative Research on Brain Tumor Diagnosis | |||
| 작성자 | 대외홍보센터 | 작성일 | 2025-03-27 |
| 조회수 | 31 | ||
| Lim Hae-kyun | International Collaborative Research on Brain Tumor Diagnosis | |||||
 |
대외홍보센터 |  |
2025-03-27 |  |
31 |
Pukyong National University, Pusan National University, and the French National Centre for Scientific Research Present International Collaborative Research on Nanophotonics Brain Tumor Diagnosis Strategy
- Pukyong National University's Professor Lim Hae-kyun and the team publish review article in the international journal <Journal of Nanobiotechnology>
A research team led by Professor Haekyun Lim of the Department of Medical Engineering at Pukyong National University's Smart Healthcare Department has attracted attention for presenting a brain tumor diagnosis and treatment strategy using nanophotonics-based photoacoustic brain imaging technology.
The international collaborative research team, including Professor Lim Hae-kyun of Pukyong National University, Dr. Badrinathan Sridharan, Master's student Park Jin-Hyung, Doctoral student Kim Dae-Hoon, Professor Kim Kwang-Seok from Pusan National University (Department of Photonics and Mechatronics Engineering), and Professor Jean-Claude Vial from the French National Centre for Scientific Research, published a review paper titled ‘Nanophotonic-enhanced photoacoustic imaging for brain tumor detection’ in the international journal <Journal of Nanobiotechnology> (IF: 10.6) in March. This journal is a highly regarded publication in the biotechnology field, ranking in the top 4.6%.
Photoacoustic brain imaging technology combines the optical contrast of laser light with the superior tissue penetration of ultrasound, enabling non-invasive, high-resolution real-time imaging of tumors and neurovascular structures within the brain.
The research team integrated nanophotonics, a technology that controls the interaction between light and matter at the nanometer scale, with photoacoustic brain imaging. By using various nanomaterials (such as gold nanoparticles and organic nanoparticles), they amplified the photoacoustic signal, presenting a method for achieving even more precise brain tissue imaging.
Additionally, the team proposed effective methods to overcome physiological barriers such as the blood-brain barrier (BBB) and blood-tumor barrier (BTB), which are obstacles to brain tumor treatment, thereby improving drug delivery efficiency for brain tumor therapy.
In particular, they highlighted a method where ultrasound is used to temporarily open the blood-brain barrier using nanoparticles, allowing drugs or nanomaterials to be precisely and effectively delivered to the brain tumor site.
Professor Lim Hae-kyun stated, "We expect that photoacoustic brain imaging technology, when integrated with existing medical imaging technologies like MRI, CT, and PET, will significantly improve the accuracy of brain tumor diagnosis and treatment monitoring, leading to innovative advancements in various brain disease treatments."
Meanwhile, the international research team (led by Professor Kim Gwang-seok) that conducted this study is operating under the 'BrainLink' project funded by the Ministry of Science and ICT and supported by the Korean Research Foundation. The team is building a collaborative research network with international competitiveness in the field of nanophotonics, based on various organic, inorganic, and bio-nanomaterials, and is currently conducting joint research. <Pukyong Today>